How Bacteria Make Toxic Lipids That Cause Disease

Grant number: 628640 | Funding period: 2010 - 2012

Completed

Abstract

Some major infectious diseases such as tuberculosis are caused by bacteria that make very unusual lipids (fats) that can kill human cells or interfere with the human immune system. The aim of this project is to work out how bacteria make these lipids. This knowledge will open up new avenues for treatments to stop bacterial lipid production and prevent disease. There are also potential applications in harnessing the bacterial lipid machinery to make new drugs and a wide range of other chemicals.

University of Melbourne Researchers